Description

5-Aminoisophthalonitrile is a high-value aromatic nitrile derivative featuring an amino functional group, serving as a critical building block in advanced organic synthesis. Its bifunctional nature makes it an indispensable precursor for constructing complex heterocyclic systems and functional polymers. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, anti-cancer agents, and other nitrogen-containing heterocyclic active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific aromatic amine-nitrile scaffolds.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for the development of high-temperature resistant polyimides, polyamides, and other specialty engineering plastics.
• Dye & Pigment Manufacturing: Acts as an intermediate for creating advanced organic pigments and colorants with enhanced stability and chromatic properties.
• Ligand & Chelator Synthesis: Utilized in the preparation of complexing agents and ligands for catalysis and metal-organic frameworks (MOFs).
• Research & Development: A versatile reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and synthetic chemistry.

Basic Information

Product Name	5-Aminoisophthalonitrile
CAS No.	57369-97-8
Molecular Formula	C8H5N3
Molecular Weight	143.15 g/mol
Synonyms	5-Amino-1,3-benzenedicarbonitrile; 5-Amino-isophthalodinitrile; 5-Aminobenzene-1,3-dicarbonitrile; 3-Amino-5-cyanobenzonitrile; Isophthalonitrile, 5-amino-; 1,3-Dicyano-5-aminobenzene; AIBN (context-specific); 5-Amino-m-phthalonitrile
EINECS	Contact for details

Quality Control

Our 5-Aminoisophthalonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	215 - 220 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.