Description

3α,6α-Bis(Trimethylsiloxy)-5β-Pregnan-20-One o-Benzyl Oxime is a high-purity, synthetic steroid derivative characterized by its specific trimethylsilyl (TMS) ether and oxime functional groups. This compound is a critical advanced intermediate in the pharmaceutical synthesis of complex steroid-based active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and production of specialized therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid hormones and related therapeutic compounds.
• Research & Development: Used in academic and industrial laboratories for investigating novel steroid pathways and creating new chemical entities for biological screening.
• Fine Chemical Synthesis: Serves as a precursor for the manufacture of high-value, specialty chemicals with specific stereochemical configurations.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of steroid-derived APIs.

Basic Information

Product Name	3α,6α-Bis(Trimethylsiloxy)-5β-Pregnan-20-One o-Benzyl Oxime
CAS No.	57326-07-5
Molecular Formula	C33H55NO3Si2
Molecular Weight	569.97 g/mol
Synonyms	3α,6α-Bis(trimethylsilyloxy)-5β-pregnan-20-one O-benzyloxime; 5β-Pregnan-20-one, 3,6-bis[(trimethylsilyl)oxy]-, O-(phenylmethyl)oxime, (3α,5β,6α)-; 3α,6α-Bis-O-(trimethylsilyl)-5β-pregnan-20-one O-benzyloxime; Pregnane-3,6-diol, 20-oxime O-benzyl ether, 3,6-bis(trimethylsilyl) ether, (3α,5β,6α)-; Steroid TMS ether oxime intermediate
EINECS	Contact for details

Quality Control

Our 3α,6α-Bis(Trimethylsiloxy)-5β-Pregnan-20-One o-Benzyl Oxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.