Description

[(20R)-5α-Pregnane-3β,11β,20,21-Tetryl]Tetra(Oxy)]Tetrakis(Trimethylsilane) CAS NO 57325-85-6 is a high-purity, fully protected steroid derivative, specifically a tetrakis(trimethylsilyl) ether of a pregnane tetrol. This compound is a critical advanced pharmaceutical intermediate and a versatile building block in complex organic synthesis. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of novel steroid-based therapeutics and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the multi-step synthesis of complex steroid hormones and their analogs for therapeutic applications.
• Organic Synthesis Building Block: Used in research and development for constructing complex molecular architectures, leveraging its protected hydroxyl groups for selective reactions.
• Steroid Chemistry Research: Essential reagent in academic and industrial laboratories for studying steroid metabolism, structure-activity relationships (SAR), and developing new synthetic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Production: Intermediate in the manufacture of specialized fine chemicals and advanced materials requiring precise steroid frameworks.

Basic Information

Product Name	[(20R)-5α-Pregnane-3β,11β,20,21-Tetryl]Tetra(Oxy)]Tetrakis(Trimethylsilane)
CAS No.	57325-85-6
Molecular Formula	C40H84O4Si4
Molecular Weight	741.43 g/mol
Synonyms	5α-Pregnane-3β,11β,20,21-tetrol, tetra-TMS derivative; 3β,11β,20,21-Tetrakis(trimethylsilyloxy)-5α-pregnane; (20R)-5α-Pregnane-3β,11β,20,21-tetrayl tetraoxytetrakis(trimethylsilane); Pregnane-3,11,20,21-tetrol TMS ether; Tetrakis-O-(trimethylsilyl) derivative of 5α-pregnane-3β,11β,20,21-tetrol
EINECS	Contact for details

Quality Control

Our [(20R)-5α-Pregnane-3β,11β,20,21-Tetryl]Tetra(Oxy)]Tetrakis(Trimethylsilane) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile and moisture-sensitive nature (as trimethylsilyl ethers), the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.