Description

3β,16β-Bis(Trimethylsiloxy)Androst-5-En-17-One o-Benzyl Oxime is a high-purity, advanced steroid intermediate featuring trimethylsilyl (TMS) protecting groups. This compound is critical for synthetic chemists requiring precise control over steroid functionalization, particularly in the synthesis of complex pharmaceutical targets. It is primarily utilized by research institutions and pharmaceutical development teams working on novel therapeutic agents, including hormone modulators and anti-inflammatory drugs.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new drug candidates targeting hormonal pathways.
• Process Chemistry: Serves as a protected intermediate in scalable manufacturing processes for steroid derivatives.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional labs for studying steroid chemistry, reaction mechanisms, and protecting group strategies.

Basic Information

Product Name	3β,16β-Bis(Trimethylsiloxy)Androst-5-En-17-One o-Benzyl Oxime
CAS No.	57305-15-4
Molecular Formula	C32H51NO3Si2
Molecular Weight	553.93 g/mol
Synonyms	Androst-5-en-17-one, 3,16-bis[(trimethylsilyl)oxy]-, O-(phenylmethyl)oxime; 3β,16β-Bis-O-(trimethylsilyl)-androst-5-en-17-one O-benzyl oxime; 3β,16β-Bis(trimethylsiloxy)androst-5-en-17-one O-benzyloxime; 57305-15-4; SCHEMBL218024; AKOS015915957; ZINC3848261; (3β,16β)-3,16-Bis(trimethylsiloxy)androst-5-en-17-one O-benzyl oxime
EINECS	Contact for details

Quality Control

Our 3β,16β-Bis(Trimethylsiloxy)Androst-5-En-17-One o-Benzyl Oxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.