Description

3-Methylcyclobutane-1-Carboxylic Acid is a specialized cyclobutane derivative carboxylic acid, serving as a valuable chiral building block and intermediate in advanced organic synthesis. Its constrained cyclobutane ring structure imparts unique steric and electronic properties, making it crucial for modulating the three-dimensional conformation and activity of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, as well as in materials science for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in creating molecules with specific stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the cyclobutane core contributes to biological activity and environmental profile.
• Liquid Crystal & Advanced Material Precursor: Serves as a building block for synthesizing mesogens and other specialty organic materials with tailored optical and electronic properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for studying ring-strain reactions, asymmetric synthesis, and as a ligand precursor in catalyst design.
• Flavor & Fragrance Ingredient Intermediate: Used in the synthesis of complex aroma chemicals that benefit from the unique structural motif of the methylcyclobutane ring.

Basic Information

Product Name	3-Methylcyclobutane-1-Carboxylic Acid
CAS No.	57252-83-2
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	3-Methylcyclobutanecarboxylic Acid; (±)-3-Methylcyclobutanecarboxylic Acid; 3-Methyl-1-cyclobutanecarboxylic Acid; 3-Methylcyclobutylcarboxylic Acid; NSC 169009; 3-Methylcyclobutane Carboxylic Acid; Cyclobutanecarboxylic acid, 3-methyl-; 3-Methyl-cyclobutanecarbonsäure (German)
EINECS	Contact for details

Quality Control

Our 3-Methylcyclobutane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, enantiomeric excess (if applicable), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.