Description

(-)-n-Dodecyl-n-Methylephedrinium Bromide is a high-purity quaternary ammonium salt derived from ephedrine, serving as a specialized chiral cationic surfactant and phase-transfer catalyst. This compound is valued for its ability to impart stereoselectivity and enhance reaction rates in asymmetric synthesis and other critical chemical processes. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced organic synthesis sectors who require precise chiral induction and efficient interfacial catalysis.

Application

• Asymmetric Synthesis: Employed as a chiral phase-transfer catalyst (PTC) for enantioselective alkylation, epoxidation, and other carbon-carbon bond-forming reactions.
• Pharmaceutical Intermediates: Used in the stereocontrolled synthesis of active pharmaceutical ingredients (APIs) where specific enantiomeric purity is critical.
• Agrochemical Production: Facilitates the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Specialty Surfactant: Acts as a chiral surfactant in micellar catalysis and in the formulation of specialized emulsions.
• Academic & Industrial Research: A key reagent for methodological development in organic chemistry and process chemistry R&D.
• Polymer Chemistry: Can be utilized in the synthesis of chiral ionic liquids or as a templating agent for materials science applications.

Basic Information

Product Name	(-)-n-Dodecyl-n-Methylephedrinium Bromide
CAS No.	57155-63-2
Molecular Formula	C22H40BrNO
Molecular Weight	414.46 g/mol
Synonyms	(-)-N-Dodecyl-N-methylephedrinium Bromide; (1R,2S)-N-Dodecyl-N-methylpseudoephedrinium Bromide; Dodecylmethylephedrinium Bromide; (1R,2S)-2-(Methylamino)-1-phenyl-1-propanol Dodecyl Methyl Ether Bromide; L-Ephedrine N-Dodecyl-N-methyl Quaternary Ammonium Bromide; Chiral Quaternary Ammonium Salt PTC; (1R,2S)-N-Methyl-N-dodecylephedrinium Bromide
EINECS	Contact for details

Quality Control

Every batch of (-)-n-Dodecyl-n-Methylephedrinium Bromide is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and chiral integrity. Our quality assurance protocol includes advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.