Description

3-Chloro-1-((4-Methylphenyl)Sulfonyl)Acetone is a specialized organic sulfone derivative of significant interest in advanced chemical synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Its unique structure, featuring both a reactive chloroacetone moiety and a tosyl-like protecting/activating group, makes it an essential intermediate for researchers and manufacturers requiring high-purity synthetic precursors.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing sulfonamide or sulfone functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Serves as an alkylating agent or a precursor for heterocyclic compounds in academic and industrial R&D laboratories.
• Material Science Research: Potential intermediate in the development of specialty polymers, dyes, and photoinitiators.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	3-Chloro-1-((4-Methylphenyl)Sulfonyl)Acetone
CAS No.	57122-47-1
Molecular Formula	C10H11ClO3S
Molecular Weight	246.71 g/mol
Synonyms	1-Chloro-3-((p-tolyl)sulfonyl)acetone; 3-Chloro-1-(p-toluenesulfonyl)acetone; 3-Chloro-1-(4-methylphenylsulfonyl)propan-2-one; 3-Chloro-1-tosylacetone; 2-Propanone, 3-chloro-1-[(4-methylphenyl)sulfonyl]-; Acetone, 3-chloro-1-((4-methylphenyl)sulfonyl)-; p-Toluenesulfonylchloroacetone
EINECS	Contact for details

Quality Control

Our 3-Chloro-1-((4-Methylphenyl)Sulfonyl)Acetone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.