Description

2-Bromobenzimidamide Hydrochloride is a high-purity organic bromide salt, serving as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile intermediate for constructing complex heterocyclic structures and active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new molecules and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel benzimidazole-based drug candidates, including potential kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in developing new fungicides and herbicides by acting as a core moiety for bioactive molecule design.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) and nucleophilic substitution reactions to introduce the amidine functionality.
• Chemical Biology & Proteomics: Serves as a reagent for modifying proteins or creating activity-based probes that target serine proteases due to the reactive amidine group.
• Material Science Research: Investigated as a monomer or additive in the synthesis of specialized polymers and organic electronic materials.

Basic Information

Product Name	2-Bromobenzimidamide Hydrochloride
CAS No.	57075-82-8
Molecular Formula	C7H8BrN2•HCl
Molecular Weight	249.52 g/mol
Synonyms	2-Bromobenzene-1-carboximidamide hydrochloride; 2-Bromobenzamidine hydrochloride; Benzenecarboximidamide, 2-bromo-, hydrochloride (1:1); (2-Bromophenyl)methanimidamide hydrochloride; 2-Bromo-benzamidine HCl; 2-Bromobenzimidamide HCl; 2-Bromobenzamidine monohydrochloride; α-Bromobenzamidine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Bromobenzimidamide Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and production use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.