Description

3',5'-Di-o-Mesylthymidine is a key nucleoside derivative and a vital chemical intermediate in organic synthesis. This compound is essential for researchers and manufacturers developing advanced pharmaceutical compounds, particularly in the fields of antiviral and anticancer drug discovery. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical synthesis industries for the production of modified nucleosides and oligonucleotides.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used in the preparation of modified DNA/RNA strands for research and therapeutic applications.
• Prodrug Development: Serves as a precursor for creating prodrugs with enhanced bioavailability and targeted delivery.
• Biochemical Research: Employed in studies investigating nucleotide metabolism, enzyme mechanisms, and nucleic acid chemistry.
• Fine Chemical Synthesis: A versatile reagent for introducing specific functional groups into complex molecular architectures.
• Antisense Therapy Development: Used in the research and production of antisense oligonucleotides for genetic medicine.

Basic Information

Product Name	3',5'-Di-o-Mesylthymidine
CAS No.	56822-33-4
Molecular Formula	C13H18N2O8S2
Molecular Weight	394.42 g/mol
Synonyms	Thymidine-3',5'-dimethanesulfonate; 3',5'-Di-O-methanesulfonylthymidine; 3',5'-Bis-O-(methylsulfonyl)thymidine; 1-[(2R,4S,5R)-4-(Methylsulfonyloxy)-5-[(methylsulfonyloxy)methyl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 3',5'-Dimesylthymidine; 3',5'-O-Dimesylthymidine; 3',5'-Dimethanesulfonylthymidine
EINECS	Contact for details

Quality Control

Our 3',5'-Di-o-Mesylthymidine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and GMP-grade synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.