Description

N2,N5-Bis(1-Methylethyl)-L-Ornithine 1-Methylethyl Ester is a protected derivative of the amino acid L-ornithine, featuring isopropyl protecting groups on the amine functionalities. This compound is a critical building block in organic synthesis, particularly valued for its role in the preparation of complex peptides and peptidomimetics. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity, specialized intermediates for drug discovery and development processes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce the L-ornithine residue with orthogonal protection.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Research: Employed in the study of enzyme inhibitors, receptor ligands, and other biologically active molecules that incorporate polyamine structures.
• Catalyst and Ligand Preparation: Can be utilized in the synthesis of novel chiral catalysts or ligands for asymmetric synthesis.

Basic Information

Product Name	N2,N5-Bis(1-Methylethyl)-L-Ornithine 1-Methylethyl Ester
CAS No.	56771-70-1
Molecular Formula	C14H30N2O2
Molecular Weight	258.40 g/mol
Synonyms	L-Ornithine, N2,N5-bis(1-methylethyl)-, 1-methylethyl ester; N(α),N(δ)-Diisopropyl-L-ornithine isopropyl ester; Diisopropyl-L-ornithine isopropyl ester; H-Orn(Di-ipr)-Oipr; (S)-2,5-Bis(isopropylamino)pentanoic acid isopropyl ester; N2,N5-Diisopropyl-L-ornithine isopropyl ester; Nα,Nδ-Diisopropyl-L-ornithine isopropyl ester
EINECS	Contact for details

Quality Control

Our N2,N5-Bis(1-Methylethyl)-L-Ornithine 1-Methylethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.