Description

Ac-Ile-Nh2 is a protected amino acid derivative, specifically N-Acetyl-L-isoleucine amide, widely utilized as a key building block in peptide synthesis and pharmaceutical research. This high-purity intermediate is critical for ensuring the structural integrity and biological activity of complex peptide chains. It is primarily sought after by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in the production of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Peptide Synthesis: A fundamental building block (amino acid derivative) for the solid-phase and solution-phase synthesis of custom and therapeutic peptides.
• Pharmaceutical Intermediates: Serves as a crucial precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and hormonal therapies.
• Biochemical Research: Used in proteomics and enzymology studies to investigate enzyme-substrate interactions and protein folding mechanisms.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for high-throughput screening in drug discovery programs.
• Reference Standard: Functions as a chromatographic or spectroscopic standard for quality control and analytical method development in QC laboratories.

Basic Information

Product Name	Ac-Ile-Nh2
CAS No.	56711-06-9
Molecular Formula	C8H16N2O2
Molecular Weight	172.23 g/mol
Synonyms	N-Acetyl-L-isoleucinamide; N-Acetyl-L-isoleucine amide; Ac-L-Ile-NH2; (2S,3S)-2-Acetamido-3-methylpentanamide; N-Acetylisoleucinamide; L-Isoleucine, N-acetyl-, amide; Nα-Acetyl-L-isoleucinamide
EINECS	Contact for details

Quality Control

Our Ac-Ile-Nh2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' compliance needs in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.