Description

3-Iodocyclohex-2-enone is a versatile halogenated cyclic enone building block, essential for advanced organic synthesis. Its unique structure, featuring both an iodine atom and an α,β-unsaturated ketone moiety, makes it a valuable electrophile and precursor for cross-coupling reactions. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, including heterocycles and natural product analogs.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized cyclohexane or heterocyclic rings.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that require halogenated ketone precursors.
• Material Science: Serves as a monomer or cross-linking agent in the research of specialty polymers with unique optical or electronic properties.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to introduce the iodocyclohexenone fragment into more complex molecules.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study enzyme mechanisms or protein-ligand interactions.
• Academic & Contract Research: A fundamental reagent for methodological studies in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	3-Iodocyclohex-2-enone
CAS No.	56671-82-0
Molecular Formula	C6H7IO
Molecular Weight	222.03 g/mol
Synonyms	3-Iodocyclohex-2-en-1-one; 3-Iodocyclohex-2-enone; 2-Cyclohexen-1-one, 3-iodo-; 3-Iodo-2-cyclohexen-1-one; 3-Iodocyclohexenone; NSC 403819
EINECS	Contact for details

Quality Control

Our 3-Iodocyclohex-2-enone is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.