Description

2,3-Dibromotetrahydro-2H-Pyran is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its ability to act as a reactive intermediate for introducing functionalized pyran rings and bromine atoms into complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those containing functionalized tetrahydropyran scaffolds common in bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the bromine atoms allow for further functionalization.
• Organic Synthesis Building Block: A valuable reagent for constructing complex organic molecules via nucleophilic substitution or coupling reactions, leveraging the reactivity of the bromine substituents.
• Material Science Research: Employed in the development of specialty polymers and advanced materials that require brominated or heterocyclic components.
• Cross-Coupling Reactions: Acts as a substrate in metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form carbon-carbon bonds.
• Ligand and Catalyst Development: Useful for synthesizing novel chiral ligands or catalyst frameworks based on the modified pyran structure.

Basic Information

Product Name	2,3-Dibromotetrahydro-2H-Pyran
CAS No.	56660-59-4
Molecular Formula	C5H8Br2O
Molecular Weight	243.93 g/mol
Synonyms	2,3-Dibromotetrahydropyran; 2,3-Dibromo-3,4-dihydro-2H-pyran; Tetrahydro-2H-pyran, 2,3-dibromo-; 2,3-Dibromotetrahydro-2H-pyran; 2H-Pyran, tetrahydro-2,3-dibromo-
EINECS	Contact for details

Quality Control

Our 2,3-Dibromotetrahydro-2H-Pyran is produced and handled under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by GC or HPLC) and impurity profiles are available upon request, supporting your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to the bromine substituents, it should be stored separately from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.