Description

5-(1-Propynyl)-2-Thiophenecarbaldehyde 2,4-Dinitrophenyl Hydrazone is a specialized organic derivative primarily used as a key analytical reagent and synthetic intermediate. Its value lies in its role as a derivatization agent for the sensitive detection and quantification of carbonyl compounds, particularly aldehydes and ketones, via HPLC and spectrophotometric methods. This compound is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and fine chemical industries who require precise analytical standards and high-purity building blocks for heterocyclic chemistry.

Application

• Analytical Derivatization Reagent: Used for the pre-column derivatization of aldehydes and ketones to enhance their detection sensitivity in High-Performance Liquid Chromatography (HPLC) and UV-Vis spectroscopy.
• Pharmaceutical Impurity Profiling: Employed in the identification and quantification of carbonyl-containing impurities or degradation products in active pharmaceutical ingredients (APIs) and drug formulations.
• Food and Environmental Analysis: Applied in methods to detect trace levels of harmful carbonyl compounds, such as formaldehyde or acetaldehyde, in food products, packaging materials, and environmental samples.
• Synthetic Intermediate: Serves as a versatile building block in organic synthesis for the construction of more complex thiophene-based molecules, including pharmaceuticals and functional materials.
• Research Chemical: Utilized in academic and industrial R&D for studying reaction mechanisms, developing new analytical methodologies, and exploring novel heterocyclic compounds.
• Quality Control Standard: Acts as a certified reference material (CRM) or internal standard for calibrating analytical instruments and validating test methods in compliance with GLP/GMP guidelines.

Basic Information

Product Name	5-(1-Propynyl)-2-Thiophenecarbaldehyde 2,4-Dinitrophenyl Hydrazone
CAS No.	56588-22-8
Molecular Formula	C15H12N4O4S
Molecular Weight	344.35 g/mol
Synonyms	5-(Prop-1-yn-1-yl)thiophene-2-carbaldehyde 2,4-dinitrophenylhydrazone; 2,4-DNPH derivative of 5-(1-Propynyl)-2-thiophenecarbaldehyde; 5-(Propynyl)thiophene-2-carboxaldehyde 2,4-dinitrophenylhydrazone; Thiophene-2-carbaldehyde, 5-(1-propynyl)-, 2,4-dinitrophenylhydrazone; 5-Propynyl-2-thiophenecarboxaldehyde 2,4-DNPH; DNPH derivative of 5-Propynyl-2-thiophenecarbaldehyde
EINECS	Contact for details

Quality Control

Our 5-(1-Propynyl)-2-Thiophenecarbaldehyde 2,4-Dinitrophenyl Hydrazone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for analytical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and physical data is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to prevent degradation. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.