Description

(+)-3,4-Dihydro-3-(4-Hydroxy-2,3-Dimethoxyphenyl)-2H-1-Benzopyran-7-Ol is a high-purity chiral flavan derivative, a key structural motif in natural products and medicinal chemistry. This compound is valued for its role as a versatile synthetic intermediate and a reference standard in analytical research. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel bioactive molecules, particularly in the areas of antioxidant and neuroprotective agents. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of complex natural product analogs and potential drug candidates.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and NMR for method development, validation, and quality control of related compounds.
• Biochemical Research: Employed in studies investigating the biological activity of flavan derivatives, including antioxidant, anti-inflammatory, and enzyme inhibition assays.
• Organic Synthesis: Acts as a chiral starting material or precursor for constructing more complex heterocyclic and polycyclic frameworks in academic and industrial research.
• Nutraceutical Research: Studied for its potential application as a bioactive component in advanced dietary supplements and functional foods.

Basic Information

Product Name	(+)-3,4-Dihydro-3-(4-Hydroxy-2,3-Dimethoxyphenyl)-2H-1-Benzopyran-7-Ol
CAS No.	56499-30-0
Molecular Formula	C₁₇H₁₈O₅
Molecular Weight	302.32 g/mol
Synonyms	(+)-7-Hydroxy-3-(4-hydroxy-2,3-dimethoxyphenyl)chroman; (3S)-3,4-Dihydro-3-(4-hydroxy-2,3-dimethoxyphenyl)-2H-1-benzopyran-7-ol; (S)-3,4-Dihydro-3-(4-hydroxy-2,3-dimethoxyphenyl)-2H-1-benzopyran-7-ol; Flavan-7-ol derivative; 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxy-2,3-dimethoxyphenyl)-, (3S)-; A flavan neolignan precursor
EINECS	Contact for details

Quality Control

Every batch of (+)-3,4-Dihydro-3-(4-Hydroxy-2,3-Dimethoxyphenyl)-2H-1-Benzopyran-7-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) including results for assay, chiral purity, and related substances is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.