Description

3-Nitrobenzamidine Hydrochloride is a high-purity organic chemical intermediate essential for advanced synthesis. This compound is valued for its role as a key building block in the creation of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals. Its consistent quality and reliable performance make it a critical component for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing benzamidine or nitro-aromatic motifs.
• Protease Inhibitor Research: Serves as a key scaffold in the development and study of synthetic protease inhibitors for therapeutic applications.
• Chemical Biology & Medicinal Chemistry: Used as a versatile building block in combinatorial chemistry and for creating targeted molecular libraries for drug discovery.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the nitrobenzamidine functional group into more complex specialty chemicals.
• Bioconjugation & Labeling Reagents: Can be utilized in the development of reagents for modifying biomolecules, leveraging its reactive amidine group.

Basic Information

Product Name	3-Nitrobenzamidine Hydrochloride
CAS No.	56406-50-9
Molecular Formula	C7H8N3O2 • HCl
Molecular Weight	217.62 g/mol
Synonyms	3-Nitrobenzenecarboximidamide Hydrochloride; m-Nitrobenzamidine Hydrochloride; Benzenecarboximidamide, 3-nitro-, hydrochloride; 3-Nitrobenzamidine HCl; 3-Nitrobenzamidine Monohydrochloride; (3-Nitrophenyl)methanimidamide Hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Nitrobenzamidine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to confirm identity and meet stringent impurity profiles. Certificates of Analysis (COA) detailing all quality parameters are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.