Description

5-Amino-1H-imidazole-4-carboxamide tetrakis(trimethylsilyl) derivative is a key silylated intermediate in advanced organic synthesis. This compound matters for its role in protecting sensitive functional groups, facilitating complex multi-step reactions with high selectivity and yield. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel heterocyclic compounds, including purine analogs and nucleoside derivatives.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of purine-based active pharmaceutical ingredients (APIs) and nucleoside analogs.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators with imidazole core structures.
• Organometallic Chemistry: Serves as a precursor for ligands in catalytic systems due to its protected, reactive nitrogen sites.
• Nucleic Acid Chemistry: Employed in the preparation of modified nucleosides and nucleotides for biochemical research and diagnostic applications.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers and advanced organic materials.
• Process Chemistry: Enables scalable, efficient synthetic routes by providing a stable, soluble form of a reactive amino-imidazole carboxamide moiety.

Basic Information

Product Name	5-Amino-1H-Imidazole-4-Carboxamide Tetrakis(Trimethylsilyl) Deriv.
CAS No.	56272-85-6
Molecular Formula	C16H40N4O1Si4
Molecular Weight	416.86 g/mol
Synonyms	5-Amino-1H-imidazole-4-carboxamide, tetrakis(trimethylsilyl) derivative; 5-Aminoimidazole-4-carboxamide Tetrakis(trimethylsilyl) Ether; AICA Tetrakis(TMS) Derivative; 4-Carbamoyl-5-aminoimidazole Tetrakis(trimethylsilyl) Ether; 5-Amino-1H-imidazole-4-carboxylic acid amide tetrakis(trimethylsilyl) derivative; Tetrakis(trimethylsilyl) 5-aminoimidazole-4-carboxamide
EINECS	Contact for details

Quality Control

Our 5-Amino-1H-imidazole-4-carboxamide tetrakis(trimethylsilyl) derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure (¹H NMR, ¹³C NMR)
Assay (HPLC)	≥ 95.0%
Purity (GC)	Residual solvents meet ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.