Description

1-O,2-O,3-O,5-o-Tetrakis(trimethylsilyl)-6-deoxy-α-L-mannofuranose is a highly specialized, protected carbohydrate derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a robust, multi-protected mannose scaffold that enables precise and selective chemical transformations. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of complex nucleosides, glycoconjugates, and other bioactive molecules where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Glycochemistry Research: Used as a protected precursor for the controlled assembly of oligosaccharides and glycopeptides.
• Process Chemistry: Enables scalable, multi-step synthesis routes requiring selective deprotection of specific hydroxyl groups.
• Carbohydrate Chemistry: Fundamental reagent for studying glycosylation reactions and anomerization processes.
• Fine Chemical Synthesis: Intermediate in the production of chiral ligands, catalysts, and specialty surfactants.
• Diagnostic Reagent Development: Potential use in creating labeled sugar derivatives for biochemical assays and imaging.

Basic Information

Product Name	1-O,2-O,3-O,5-o-Tetrakis(trimethylsilyl)-6-deoxy-α-L-mannofuranose
CAS No.	56227-38-4
Molecular Formula	C18H44O5Si4
Molecular Weight	464.88 g/mol
Synonyms	6-Deoxy-α-L-mannofuranose, 1,2,3,5-tetrakis-O-(trimethylsilyl)-; α-L-6-Deoxymannofuranose 1,2,3,5-tetrakis(trimethylsilyl) ether; Tetrakis-O-trimethylsilyl-6-deoxy-α-L-mannofuranose; 6-Deoxy-1,2,3,5-tetra-O-trimethylsilyl-α-L-mannofuranose; Protected 6-deoxy-L-mannose; TMS-protected 6-deoxy-mannose derivative; Per-O-trimethylsilylated 6-deoxy-α-L-mannofuranose
EINECS	Contact for details

Quality Control

Our production of 1-O,2-O,3-O,5-o-Tetrakis(trimethylsilyl)-6-deoxy-α-L-mannofuranose adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.