Description

2-Amino-1-O,3-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-2-Deoxy-D-Glucitol is a key protected carbohydrate derivative, specifically a fully silylated amino sugar alcohol. This compound is highly valued as a crucial synthetic intermediate and protecting group strategy in advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the construction of complex bioactive molecules, particularly in carbohydrate and nucleoside chemistry.

Application

• Pharmaceutical Intermediate: Serves as a protected building block for the synthesis of novel glycosidase inhibitors, antiviral agents, and other carbohydrate-based therapeutics.
• Nucleoside & Nucleotide Chemistry: Used in the preparation of modified sugar moieties for antisense oligonucleotides and prodrug development.
• Glycoconjugate Synthesis: Acts as a key precursor in the controlled synthesis of complex oligosaccharides and glycoconjugates for biological studies.
• Chiral Auxiliary & Ligand Synthesis: Provides a chiral scaffold for the development of asymmetric catalysts and ligands in enantioselective synthesis.
• Agrochemical Research: Employed in the discovery and development of new carbohydrate-derived active ingredients.
• Process Chemistry & Scale-up: Offers a stable, protected form of a reactive amino sugar for robust multi-step synthetic routes in kilo-lab and pilot plant operations.

Basic Information

Item	Detail
Product Name	2-Amino-1-O,3-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-2-Deoxy-D-Glucitol
CAS No.	56196-64-6
Molecular Formula	C23H57NO5Si5
Molecular Weight	584.18 g/mol
Synonyms	2-Amino-2-deoxy-D-glucitol pentakis(trimethylsilyl) ether; 2-Amino-1,3,4,5,6-penta-O-trimethylsilyl-2-deoxy-D-glucitol; 2-Amino-2-deoxy-D-glucitol, 1,3,4,5,6-pentakis-O-(trimethylsilyl)-; Fully TMS-protected 2-amino-2-deoxy-D-glucitol; Pentakis(trimethylsilyl) 2-amino-2-deoxy-D-glucitol; TMS-protected glucosaminitol; 2-Amino-1,3,4,5,6-penta-O-TMS-2-deoxy-D-glucitol
EINECS	Contact for details

Quality Control

Our production of 2-Amino-1-O,3-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-2-Deoxy-D-Glucitol adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.