Description

[(4-Nitrophenyl)Sulfonyl]Methyltrifluoromethanesulfonate is a specialized sulfonate ester derivative, valued for its role as a versatile electrophilic reagent and building block in advanced organic synthesis. This compound is particularly significant for introducing the [(4-nitrophenyl)sulfonyl]methyl (Nosylmethyl) group, a useful protecting and functionalizing moiety. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing functionalized methylene groups.
• Protecting Group Chemistry: Serves as a reagent for the introduction of the 4-nitrobenzenesulfonyl (Nosyl) protecting group for amines and other nucleophiles in multi-step syntheses.
• Alkylation Agent: Used as an electrophilic alkylating agent in C-C and C-heteroatom bond-forming reactions under controlled conditions.
• Polymer Chemistry: Potential monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes and labeled compounds for biochemical research.
• Agrochemical Synthesis: Intermediate in the research and development of novel crop protection agents and herbicides.

Basic Information

Product Name	[(4-Nitrophenyl)Sulfonyl]Methyltrifluoromethanesulfonate
CAS No.	56177-36-7
Molecular Formula	C8H6F3NO7S2
Molecular Weight	349.26 g/mol
Synonyms	Methyl [(4-Nitrophenyl)Sulfonyl] Trifluoromethanesulfonate; Nosylmethyl Triflate; 4-Nitrobenzenesulfonylmethyl Trifluoromethanesulfonate; (4-Nitrobenzenesulfonyl)methyl Triflate; Trifluoromethanesulfonic Acid (4-Nitrobenzenesulfonyl)methyl Ester; 1-[(Trifluoromethylsulfonyl)oxy]methanesulfonyl-4-nitrobenzene
EINECS	Contact for details

Quality Control

Our [(4-Nitrophenyl)Sulfonyl]Methyltrifluoromethanesulfonate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its reactivity as a strong acid derivative and sensitivity to moisture, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.