Description

5-Hydroxy-1-Benzofuran-2-Carboxylic Acid is a high-purity benzofuran derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique fused-ring structure with both phenolic and carboxylic acid functionalities makes it a versatile building block for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Research: Building block for developing new-generation herbicides and fungicides with enhanced efficacy and selectivity.
• Material Science: Used in the synthesis of organic semiconductors, liquid crystals, and advanced polymers due to its rigid, planar benzofuran core.
• Dye & Pigment Synthesis: Intermediate for creating specialized heterocyclic dyes with specific light-absorption properties.
• Academic & R&D: Serves as a standard reagent in methodological studies and for exploring new organic reactions and catalytic processes.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing complex aroma chemicals with benzofuran motifs.

Basic Information

Product Name	5-Hydroxy-1-Benzofuran-2-Carboxylic Acid
CAS No.	56172-36-2
Molecular Formula	C9H6O4
Molecular Weight	178.14 g/mol
Synonyms	5-Hydroxybenzofuran-2-carboxylic acid; 2-Benzofurancarboxylic acid, 5-hydroxy-; 5-Hydroxycoumarilic acid; 5-Hydroxy-2-benzofurancarboxylic acid; 5-Hydroxy-2-carboxybenzofuran; 5-Hydroxybenzo[b]furan-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-1-Benzofuran-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.