Description

trans-2,5-Bis(Iodomethyl)-1,4-Dioxane is a versatile and highly functionalized organic building block characterized by its reactive iodomethyl groups and dioxane backbone. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, enabling the introduction of functional handles for further chemical elaboration. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Acts as a cross-linking agent or monomer for creating specialty polymers and functional materials.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands and organocatalysts for asymmetric synthesis.
• Chemical Research: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and reaction pathways.
• Fine Chemical Production: Utilized in the multi-step synthesis of high-value, complex fine chemicals and flavors/fragrances.

Basic Information

Product Name	trans-2,5-Bis(Iodomethyl)-1,4-Dioxane
CAS No.	56127-59-4
Molecular Formula	C6H10I2O2
Molecular Weight	367.95 g/mol
Synonyms	2,5-Bis(iodomethyl)-1,4-dioxane (trans-); 1,4-Dioxane, 2,5-bis(iodomethyl)-, trans-; trans-2,5-Diiodomethyl-1,4-dioxane; (2R,5R)-2,5-Bis(iodomethyl)-1,4-dioxane; (2S,5S)-2,5-Bis(iodomethyl)-1,4-dioxane; 2,5-Diiodomethyl-1,4-dioxane; 1,4-Dioxane-2,5-dimethanol, 2,5-diiodo-
EINECS	Contact for details

Quality Control

Our trans-2,5-Bis(Iodomethyl)-1,4-Dioxane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), related substances, and physical characteristics is provided with each shipment to guarantee it meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, prolonged exposure to light should be avoided. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.