Description

3,3-Dimethylglutaric Acid Bis(Trimethylsilyl) Ester is a high-purity silylated derivative of 3,3-dimethylglutaric acid, serving as a crucial protected intermediate in advanced organic synthesis. This compound is valued for its role in facilitating complex reactions where sensitive functional groups require protection from harsh conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly where carboxylic acid protection is required.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Peptide Chemistry: Acts as a protected dicarboxylic acid component in the synthesis of peptide analogs and mimetics.
• Polymer Science: Serves as a monomer or co-monomer precursor for the development of specialty polyesters and polyamides with unique thermal properties.
• Material Science Research: Employed in the creation of organic frameworks, dendrimers, and other advanced functional materials.
• Cross-Coupling Reactions: Useful as a substrate in palladium-catalyzed and other metal-mediated coupling reactions following deprotection.

Basic Information

Product Name	3,3-Dimethylglutaric Acid Bis(Trimethylsilyl) Ester
CAS No.	55887-57-5
Molecular Formula	C13H28O4Si2
Molecular Weight	304.53 g/mol
Synonyms	Bis(trimethylsilyl) 3,3-Dimethylglutarate; 3,3-Dimethylglutaric Acid Bis(trimethylsilyl) Ester; 3,3-Dimethylpentanedioic Acid Bis(trimethylsilyl) Ester; Glutaric acid, 3,3-dimethyl-, bis(trimethylsilyl) ester; TMS Ester of 3,3-Dimethylglutaric Acid; Silylated 3,3-Dimethylglutarate
EINECS	Contact for details

Quality Control

Our 3,3-Dimethylglutaric Acid Bis(Trimethylsilyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and HPLC analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications in cGMP environments and research requiring reliable and reproducible synthetic intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.