Description

2-(Acetylthio)Benzoic Acid is a versatile sulfur-containing benzoic acid derivative, primarily valued as a key synthetic intermediate in organic chemistry. Its unique structure, featuring both a carboxylic acid and a protected thiol group, makes it a crucial building block for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting cardiovascular, anti-inflammatory, or neurological pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the thioester moiety is incorporated into the active molecule.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Peptide Mimetics and Bioconjugation: The protected thiol group allows for selective deprotection and subsequent conjugation, useful in bioconjugation chemistry and peptide analog design.
• Material Science Research: Employed in the synthesis of functionalized polymers or organic semiconductors where sulfur-containing aromatic units are required.
• Chemical Biology Probes: Acts as a building block for creating activity-based probes or affinity labels to study enzyme function.

Basic Information

Product Name	2-(Acetylthio)Benzoic Acid
CAS No.	55819-78-8
Molecular Formula	C9H8O3S
Molecular Weight	196.22 g/mol
Synonyms	2-(Acetylthio)benzoic acid; o-(Acetylthio)benzoic acid; 2-(Acetylsulfanyl)benzoic acid; Benzoic acid, 2-(acetylthio)-; 2-Carboxyphenyl thioacetate; Acetic acid, thio-, S-(2-carboxyphenyl) ester; ATBA
EINECS	Contact for details

Quality Control

Our 2-(Acetylthio)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.