Description

Butanoic Acid, 3-[(Trimethylsilyl)Oxy]-, Ethyl Ester is a specialized organosilicon compound that serves as a valuable protected intermediate in synthetic organic chemistry. Its core value lies in the trimethylsilyl (TMS) protecting group, which shields the reactive hydroxyl functionality, enabling selective reactions in complex multi-step syntheses. This high-purity reagent is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries who require reliable, high-quality building blocks for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used as a protected synthon for introducing butanoic acid derivatives into target molecules with high selectivity.
• Peptide Chemistry: Employed in the preparation of protected amino acid derivatives and peptide fragments.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Flavor and Fragrance Industry: Potential precursor for the synthesis of specific ester-based aroma compounds.
• Material Science: Monomer or modifying agent in the synthesis of specialized silicon-containing polymers.
• Academic & R&D Laboratories: A versatile reagent for methodological development and exploratory organic synthesis.

Basic Information

Product Name	Butanoic Acid, 3-[(Trimethylsilyl)Oxy]-, Ethyl Ester
CAS No.	55816-59-6
Molecular Formula	C9H20O3Si
Molecular Weight	204.34 g/mol
Synonyms	Ethyl 3-(Trimethylsilyloxy)butyrate; 3-(Trimethylsiloxy)butyric Acid Ethyl Ester; Ethyl 3-Hydroxybutyrate Trimethylsilyl Ether; 3-[(Trimethylsilyl)oxy]butanoic Acid Ethyl Ester; TMS-Protected Ethyl 3-Hydroxybutyrate; Ethyl β-Hydroxybutyrate TMS Ether; Butanoic acid, 3-[(trimethylsilyl)oxy]-, ethyl ester; 55816-59-6
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 3-[(Trimethylsilyl)Oxy]-, Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with full traceability are provided for every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.410 - 1.420
Density (g/mL at 20°C)	0.90 - 0.95

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.