Description

5-Methyl-2-Trimethylsilyl-Furan is a specialized organosilicon reagent featuring a protected furan ring system. This compound is valued for its role as a versatile synthetic building block in advanced organic synthesis, particularly for introducing the 5-methylfuran moiety under mild conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing functionalized furan heterocycles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the furan scaffold imparts specific biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers, resins, and organic electronic materials.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the reactivity of the silyl-protected position.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes for natural product synthesis and medicinal chemistry projects requiring regioselective functionalization.
• Flavor & Fragrance Chemistry: Used in the research and development of novel flavor and aroma compounds derived from furan chemistry.

Basic Information

Product Name	5-Methyl-2-Trimethylsilyl-Furan
CAS No.	55811-60-4
Molecular Formula	C8H14OSi
Molecular Weight	154.28 g/mol
Synonyms	2-(Trimethylsilyl)-5-methylfuran; 5-Methyl-2-(trimethylsilyl)furan; 5-Methylfuran-2-yltrimethylsilane; Trimethyl(5-methyl-2-furyl)silane; 2-Trimethylsilyl-5-methylfuran; 5-Methyl-2-furyltrimethylsilane
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-Trimethylsilyl-Furan is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.