Description

1R-cis-Permethrinic Acid is a key chiral intermediate and acid metabolite of the widely used synthetic pyrethroid insecticide, permethrin. This compound matters significantly for manufacturers requiring high-purity, stereochemically defined building blocks for advanced agrochemical synthesis and environmental metabolite studies. It is primarily needed by agrochemical R&D laboratories, active ingredient producers, and analytical service providers focused on pesticide metabolism, residue analysis, and the development of next-generation insecticidal agents.

Application

• Agrochemical Intermediate: Critical chiral precursor for the synthesis of permethrin and related pyrethroid insecticides.
• Metabolite Standard: Used as an analytical reference standard in environmental and toxicological studies to track permethrin degradation and metabolism.
• Research & Development: Serves as a building block in organic synthesis for developing novel insecticidal compounds with improved efficacy or selectivity.
• Quality Control: Employed in the quality assurance processes of permethrin manufacturing to monitor reaction pathways and impurity profiles.

Basic Information

Product Name	1R-cis-Permethrinic Acid
CAS No.	55667-40-8
Molecular Formula	C21H20Cl2O3
Molecular Weight	391.29 g/mol
Synonyms	(1R,3R)-3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic Acid; (1R)-trans-Permethrinic Acid; (+)-trans-Permethrinic Acid; Cyclopropanecarboxylic acid, 3-[(1Z)-2,2-dichloroethenyl]-2,2-dimethyl-, (1R,3R)-; Permethrin Acid Metabolite; 1R-trans-Permethrinic Acid (common misnomer for the cis-isomer relative to chrysanthemic acid nomenclature); NRDC 163 acid (related series).
EINECS	Contact for details

Quality Control

Our 1R-cis-Permethrinic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); it is recommended to handle under an inert atmosphere such as nitrogen for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% (1R,3R isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.