Description

n-[1-Methoxy-2-Oxo-7-[(Trimethylsilyl)Oxy]-3,9-Dioxabicyclo[3.3.1]Nonan-6-Yl]Acetamide CAS NO 55622-39-4 is a specialized, high-purity synthetic intermediate featuring a complex bicyclic acetal structure protected by a trimethylsilyl (TMS) group. This compound is valued for its role as a key chiral building block in advanced organic synthesis, particularly for constructing complex pharmacophores. It is primarily sought by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, particularly those with carbohydrate-like or polycyclic frameworks.
• Chiral Synthesis: Utilized as a stereochemically defined building block for the asymmetric synthesis of natural products and bioactive molecules.
• Glycochemistry & Glycomimetics: Serves as a protected glycosyl donor or a scaffold for developing sugar mimetics and related bioactive compounds.
• Protecting Group Chemistry: The TMS-protected hydroxyl group allows for selective deprotection and further functionalization in complex synthetic sequences.
• Agrochemical Research: Potential intermediate in the synthesis of novel, high-performance herbicides or fungicides with specific modes of action.
• Academic & Contract Research: Used in university and CRO laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	n-[1-Methoxy-2-Oxo-7-[(Trimethylsilyl)Oxy]-3,9-Dioxabicyclo[3.3.1]Nonan-6-Yl]Acetamide
CAS No.	55622-39-4
Molecular Formula	C13H23NO6Si
Molecular Weight	317.41 g/mol
Synonyms	Acetamide, N-[1-methoxy-2-oxo-7-[(trimethylsilyl)oxy]-3,9-dioxabicyclo[3.3.1]nonan-6-yl]-; 6-Acetamido-1-methoxy-7-(trimethylsilyloxy)-3,9-dioxabicyclo[3.3.1]nonan-2-one; TMS-protected bicyclic acetamide intermediate; 1-Methoxy-2-oxo-7-(trimethylsilyloxy)-3,9-dioxabicyclo[3.3.1]nonan-6-yl acetamide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.