Description

2-(Trimethylsiloxy)-2-Pentenedioic Acid Dimethyl Ester is a specialized organosilicon reagent featuring a silyl enol ether functional group. This compound is valued for its role as a versatile synthetic intermediate, particularly in the formation of carbon-carbon bonds and the protection of carbonyl functionalities. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing complex molecular scaffolds.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides.
• Organic Synthesis Reagent: Functions as a silyl enol ether in aldol reactions, Michael additions, and other carbon-carbon bond-forming transformations.
• Carbonyl Protection: Acts as a protecting group for dicarbonyl compounds during multi-step synthetic sequences.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances.
• Material Science Research: Investigated as a precursor for novel silicon-containing polymers and hybrid materials.

Basic Information

Product Name	2-(Trimethylsiloxy)-2-Pentenedioic Acid Dimethyl Ester
CAS No.	55590-96-0
Molecular Formula	C11H20O5Si
Molecular Weight	260.36 g/mol
Synonyms	Dimethyl 2-(trimethylsiloxy)pent-2-enedioate; 2-Pentenedioic acid, 2-(trimethylsiloxy)-, dimethyl ester; (E)-Dimethyl 2-(trimethylsilyloxy)pent-2-enedioate; Silyl enol ether of dimethyl 2-oxoglutarate; Trimethylsilyl 2-(methoxycarbonyl)-3-(methoxycarbonyl)propenyl ether
EINECS	Contact for details

Quality Control

Our production of 2-(Trimethylsiloxy)-2-Pentenedioic Acid Dimethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity, purity, and absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.