Description

4-Methoxy-n-[(Pentafluorophenyl)Methylene]-3-[(Trimethylsilyl)Oxy]Benzeneethanamine CAS NO 55556-73-5 is a specialized, high-value synthetic intermediate featuring a unique molecular architecture combining pentafluorophenyl, trimethylsilyloxy, and methoxy functional groups. This compound is critical for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and advanced material science sectors seeking to incorporate fluorinated and silyl-protected motifs into complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of fluorinated drug candidates, including potential CNS agents and anti-inflammatory compounds.
• Agrochemical Research: Used in creating novel pesticides and herbicides where the pentafluorophenyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced fluorinated materials.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating fluorescent or affinity tags due to its reactive imine and silyl-protected phenol groups.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new reaction pathways in organic chemistry.

Basic Information

Product Name	4-Methoxy-n-[(Pentafluorophenyl)Methylene]-3-[(Trimethylsilyl)Oxy]Benzeneethanamine
CAS No.	55556-73-5
Molecular Formula	C19H20F5NO2Si
Molecular Weight	417.45 g/mol
Synonyms	3-[(Trimethylsilyl)oxy]-4-methoxy-N-[(pentafluorophenyl)methylene]benzeneethanamine; N-[(2,3,4,5,6-Pentafluorophenyl)methylene]-2-[3-[(trimethylsilyl)oxy]-4-methoxyphenyl]ethanamine; 2-(3-((Trimethylsilyl)oxy)-4-methoxyphenyl)-N-((perfluorophenyl)methylene)ethan-1-amine; Pentafluorobenzylidene derivative of 2-(3-Hydroxy-4-methoxyphenyl)ethylamine TMS ether; Fluorinated Schiff Base TMS Ether; CAS 55556-73-5
EINECS	Contact for details

Quality Control

Every batch of 4-Methoxy-n-[(Pentafluorophenyl)Methylene]-3-[(Trimethylsilyl)Oxy]Benzeneethanamine is produced and tested under strict quality management systems. We employ advanced analytical techniques including HPLC, GC-MS, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical parameters are provided with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.