Description

Glycine, n-(1-Oxopentyl)-n-(Trimethylsilyl)-, Trimethylsilyl Ester is a specialized organosilicon-protected amino acid derivative, primarily utilized as a key synthetic intermediate in advanced organic and medicinal chemistry. Its value lies in providing a protected glycine moiety, enabling selective reactions in complex multi-step syntheses where standard amino acid reactivity must be controlled. This compound is essential for researchers and manufacturers in the pharmaceutical industry developing novel peptide-based therapeutics and for chemists in agrochemical and material science R&D.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of modified peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators with amino acid backbones.
• Organic Synthesis Reagent: Serves as a protected glycine equivalent in complex organic transformations, including nucleophilic acyl substitutions and coupling reactions.
• Material Science Research: Employed in the development of specialized polymers, dendrimers, and surface-modifying agents where silicon and amino acid functionalities are combined.
• Bioconjugation Chemistry: Facilitates the site-specific modification of biomolecules for drug delivery systems and diagnostic probes.

Basic Information

Product Name	Glycine, n-(1-Oxopentyl)-n-(Trimethylsilyl)-, Trimethylsilyl Ester
CAS No.	55530-59-1
Molecular Formula	C13H27NO3Si2
Molecular Weight	301.53 g/mol
Synonyms	N-Pentanoyl-N-(trimethylsilyl)glycine trimethylsilyl ester; N-(1-Oxopentyl)-N-(trimethylsilyl)glycine TMS ester; Trimethylsilyl N-[trimethylsilyl(pentanoyl)amino]acetate; Glycine, N-pentanoyl-N-(trimethylsilyl)-, trimethylsilyl ester; TMS-Glycine TMS ester pentanoyl derivative; N-Trimethylsilyl-N-pentanoylglycine trimethylsilyl ester; Silylated glycine valeroyl derivative
EINECS	Contact for details

Quality Control

Our Glycine, n-(1-Oxopentyl)-n-(Trimethylsilyl)-, Trimethylsilyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.