Description

n-[(Pentafluorophenyl)Methylene]-β,4-Bis[(Trimethylsilyl)Oxy]Benzeneethanamine is a specialized organosilicon compound featuring a pentafluorophenyl group and protected phenolic functionalities. This chemical serves as a key synthetic intermediate and building block in advanced organic synthesis, valued for its unique reactivity profile. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for the development of complex molecules, including active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems.
• Advanced Organic Synthesis: Used as a protected precursor for introducing specific functional groups in multi-step synthesis for agrochemicals and specialty chemicals.
• Material Science Research: Serves as a monomer or precursor in the development of novel polymers and functional materials with specific electronic or surface properties.
• Ligand and Catalyst Development: Employed in the research and preparation of specialized ligands for catalysis, leveraging the electron-withdrawing pentafluorophenyl group.
• Fluorine Chemistry: A valuable reagent for incorporating pentafluorophenyl motifs into target molecules, which can alter lipophilicity, metabolic stability, and binding affinity.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical reactions involving silyl-protected phenols.

Basic Information

Product Name	n-[(Pentafluorophenyl)Methylene]-β,4-Bis[(Trimethylsilyl)Oxy]Benzeneethanamine
CAS No.	55429-85-1
Molecular Formula	C21H26F5NO2Si2
Molecular Weight	483.61 g/mol
Synonyms	1-[Bis(trimethylsilyloxy)(4-{[pentafluorophenyl)methylidene]amino}phenyl)methyl]-N-ethylethanamine; Benzeneethanamine, N-[(pentafluorophenyl)methylene]-β,4-bis[(trimethylsilyl)oxy]-; N-[(Pentafluorophenyl)methylidene]-β,4-bis(trimethylsilyloxy)benzeneethanamine; TMS-protected Pentafluorobenzylidene Aniline Derivative; Pentafluorophenyl Imine Silyl Ether; 55429-85-1; (Beta,4-Bis(trimethylsilyloxy)-N-(pentafluorobenzylidene)phenethylamine)
EINECS	Contact for details

Quality Control

Our n-[(Pentafluorophenyl)Methylene]-β,4-Bis[(Trimethylsilyl)Oxy]Benzeneethanamine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.