Description

1,11-Bis(Methanesulfonyloxy)-3,6,9-Trioxandecane is a specialized bifunctional methanesulfonate ester derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its ability to act as a versatile alkylating or cross-linking agent, enabling the precise construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, polymer, and specialty chemical industries who require reliable and consistent performance in demanding synthetic applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring polyether or PEG-like spacers.
• Polymer Chemistry: Used as a cross-linking agent or monomer for creating specialized polyethers, hydrogels, and functionalized polymers with tailored properties.
• Bioconjugation: Facilitates the attachment of drugs, dyes, or other molecules to proteins, antibodies, or nanoparticles via its reactive sulfonate ester groups.
• Material Science: Employed in the development of advanced materials, including surface modifiers, coatings, and dendrimers.
• Organic Synthesis: A versatile reagent for introducing protected or functionalized trioxaundecane chains into target molecules.
• Linker Chemistry: Serves as a cleavable or non-cleavable linker in prodrug design and targeted drug delivery systems.

Basic Information

Product Name	1,11-Bis(Methanesulfonyloxy)-3,6,9-Trioxandecane
CAS No.	55400-73-2
Molecular Formula	C11H24O10S2
Molecular Weight	380.43 g/mol
Synonyms	3,6,9-Trioxaundecane-1,11-diyl bis(methanesulfonate); 1,11-Bis(mesyloxy)-3,6,9-trioxaundecane; PEG-3 Dimethanesulfonate; Tetraethylene Glycol Dimethanesulfonate; Bis-Ms-Tetraethylene Glycol; 1,11-Dimesyl-3,6,9-trioxaundecane; 2,2'-(Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(methanesulfonate); Tetraethylene glycol dimesylate
EINECS	Contact for details

Quality Control

Our 1,11-Bis(Methanesulfonyloxy)-3,6,9-Trioxandecane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.