Description

[(5β-Cholestan-3β-Yl)Oxy]Trimethylsilane is a high-purity organosilicon derivative of cholestane, a key steroid backbone. This compound is valued for its role as a versatile synthetic intermediate and protecting group reagent in advanced organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel steroid-based therapeutics, fine chemicals, and complex organic molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel steroid drugs and active pharmaceutical ingredients (APIs).
• Steroid Chemistry Research: Used in academic and industrial R&D for modifying the cholestane skeleton to explore new biological activities.
• Protecting Group Reagent: The trimethylsilyl (TMS) ether group serves to protect hydroxyl functionalities during complex synthetic sequences.
• Fine Chemical Synthesis: Employed in the production of specialized chiral compounds and high-value chemical standards.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in steroid analysis.

Basic Information

Product Name	[(5β-Cholestan-3β-Yl)Oxy]Trimethylsilane
CAS No.	55331-94-7
Molecular Formula	C30H56OSi
Molecular Weight	460.86 g/mol
Synonyms	3β-(Trimethylsilyloxy)-5β-cholestane; 5β-Cholestan-3β-ol, trimethylsilyl ether; Cholestan-3β-yloxytrimethylsilane; Trimethyl(5β-cholestan-3β-yloxy)silane; 3β-TMS Ether of 5β-Cholestanol; (3β)-3-[(Trimethylsilyl)oxy]-5β-cholestane
EINECS	Contact for details

Quality Control

Our [(5β-Cholestan-3β-Yl)Oxy]Trimethylsilane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.