Description

(1S,4Aα)-5β-Carboxydecahydro-5,8Aβ-Dimethyl-2-Methylene-1-Naphthaleneacetic Acid is a high-purity, functionalized decalin derivative with significant synthetic utility. This compound serves as a versatile and valuable chiral building block and advanced pharmaceutical intermediate in complex organic synthesis. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing intricate molecular architectures, particularly in the synthesis of bioactive natural products and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in steroid-like or terpenoid-based drug candidates.
• Organic Synthesis Building Block: Utilized in asymmetric synthesis, cycloaddition reactions, and other complex transformations to introduce functionalized decalin cores.
• Agrochemical Research: Serves as a precursor in the synthesis of advanced crop protection agents and bioactive molecules with specific stereochemical requirements.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and other high-value compounds requiring precise stereochemistry.
• Academic & Industrial R&D: Used in research laboratories for methodological studies, catalyst testing, and the development of new synthetic pathways.
• Material Science Precursor: Potential starting material for synthesizing specialized polymers or liquid crystals with unique structural properties.

Basic Information

Item	Details
Product Name	(1S,4Aα)-5β-Carboxydecahydro-5,8Aβ-Dimethyl-2-Methylene-1-Naphthaleneacetic Acid
CAS No.	55306-07-5
Molecular Formula	C₁₆H₂₄O₄
Molecular Weight	280.36 g/mol
Synonyms	5β-Carboxy-5,8aβ-dimethyldecahydro-2-methylene-1-naphthaleneacetic acid; (1S,4aα,5β,8aβ)-5-Carboxy-5,8a-dimethyldecahydro-2-methylene-1-naphthaleneacetic acid; Podocarpic acid derivative; Decahydronaphthaleneacetic acid derivative; Chiral decalin dicarboxylic acid derivative. Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (1S,4Aα)-5β-Carboxydecahydro-5,8Aβ-Dimethyl-2-Methylene-1-Naphthaleneacetic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.