Description

(R)-4,4A,5,6,7,8-Hexahydro-4A,7,7-Trimethylnaphthalen-2(3H)-One is a high-purity chiral intermediate and building block of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and complex terpenoid-derived structure, which is crucial for creating optically active target molecules. This compound is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for applications such as fragrance development and the synthesis of bioactive natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for compounds with terpenoid or steroidal frameworks.
• Fragrance and Flavor Synthesis: Used as a building block for creating complex, high-value odorants and flavorants due to its camphoraceous and woody structural notes.
• Agrochemical Research: Employed in the synthesis of advanced chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Fine Chemical Manufacturing: Acts as a specialized intermediate for producing custom catalysts, ligands, and other performance chemicals requiring precise molecular architecture.
• Academic and Industrial R&D: A valuable reagent for methodological studies in asymmetric synthesis, total synthesis, and catalysis.

Basic Information

Product Name	(R)-4,4A,5,6,7,8-Hexahydro-4A,7,7-Trimethylnaphthalen-2(3H)-One
CAS No.	55123-72-3
Molecular Formula	C₁₃H₂₀O
Molecular Weight	192.30 g/mol
Synonyms	(R)-4,4a,5,6,7,8-Hexahydro-4a,7,7-trimethyl-2(3H)-naphthalenone; (R)-4,4a,5,6,7,8-Hexahydro-4a,7,7-trimethylnaphthalen-2(3H)-one; (R)-2,3,4,4a,5,6,7,8-Octahydro-4a,7,7-trimethyl-2-naphthalenone; (R)-Octahydro-4a,7,7-trimethyl-2-naphthalenone; (R)-OTNE; (R)-Iso-E Super; (R)-Iso E Super; (R)-Tetrahydro-4a,7,7-trimethyl-2-naphthalenone
EINECS	Contact for details

Quality Control

Our (R)-4,4A,5,6,7,8-Hexahydro-4A,7,7-Trimethylnaphthalen-2(3H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/GC), enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.