Description

(E)-2,2,3-Trimethyl-4-Phenyl-But-3-Enoic Acid is a high-purity, specialized organic acid derivative featuring a phenyl-substituted butenoic acid structure. This compound serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis, valued for its defined stereochemistry and functional group compatibility. It is primarily utilized by pharmaceutical R&D, agrochemical, and fine chemical manufacturers for the development of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for sterically hindered targets.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators with specific stereochemical requirements.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, fragrances, and advanced material precursors.
• Academic & Industrial Research: Valuable reagent in methodological development, catalysis studies, and asymmetric synthesis projects.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chiral ligands and organocatalysts.

Basic Information

Product Name	(E)-2,2,3-Trimethyl-4-Phenyl-But-3-Enoic Acid
CAS No.	55078-29-0
Molecular Formula	C₁₃H₁₆O₂
Molecular Weight	204.27 g/mol
Synonyms	(E)-2,2,3-Trimethyl-4-phenylbut-3-enoic acid; (E)-3,4-Dihydro-4,4-dimethyl-3-methylene-2-phenyl-2H-naphthalen-1-one (related form); α,α,β-Trimethylcinnamic acid; (E)-2,2,3-Trimethyl-4-phenyl-3-butenoic acid; trans-2,2,3-Trimethyl-4-phenyl-3-butenoic acid; 55078-29-0; But-3-enoic acid, 2,2,3-trimethyl-4-phenyl-, (E)-
EINECS	Contact for details

Quality Control

Our (E)-2,2,3-Trimethyl-4-Phenyl-But-3-Enoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.