Description

n-(2,2,2-Trifluoro-1-Methylethylidene)Benzeneethanamine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the trifluoromethyl and imine groups, enabling the construction of complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a building block for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the preparation of fluorinated polymers and specialty chemicals with unique surface properties.
• Chemical Biology Probes: Useful for synthesizing tagged molecules to study biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a trifluoromethylated amine moiety.

Basic Information

Product Name	n-(2,2,2-Trifluoro-1-Methylethylidene)Benzeneethanamine
CAS No.	54815-09-7
Molecular Formula	C11H12F3N
Molecular Weight	215.22 g/mol
Synonyms	N-(2,2,2-Trifluoro-1-methylethylidene)-2-phenylethanamine; 2-Phenylethyl(1,1,1-trifluoro-2-propanylidene)amine; 1,1,1-Trifluoro-2-(2-phenylethylimino)propane; N-(1,1,1-Trifluoro-2-propylidene)-2-phenylethylamine; α,α,α-Trifluoro-N-(2-phenylethylidene)isopropylamine; TFMPEA (abbreviation); (2,2,2-Trifluoro-1-methylethylidene)(2-phenylethyl)amine
EINECS	Contact for details

Quality Control

Our n-(2,2,2-Trifluoro-1-Methylethylidene)Benzeneethanamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive analytical data including HPLC purity, NMR, and MS confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.