Description

2-(Trimethylsiloxy)-1,3-Cyclohexadiene is a specialized organosilicon compound featuring a silyl-protected diene functionality, which serves as a versatile synthetic intermediate. Its core value lies in enabling complex organic transformations, particularly in the synthesis of natural products and pharmaceuticals, by acting as a masked synthon for reactive carbonyl equivalents. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable building blocks for sophisticated synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and natural product analogs.
• Diels-Alder Reactions: Serves as a reactive diene component in cycloaddition reactions to construct complex carbocyclic and heterocyclic ring systems.
• Silyl Enol Ether Chemistry: Utilized as a silyl enol ether equivalent in alkylation, acylation, and aldol condensation reactions under mild conditions.
• Agrochemical Synthesis: Employed in the research and development of novel active ingredients for crop protection.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials requiring specific silicon-containing precursors.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploratory chemistry in university and corporate laboratories.

Basic Information

Product Name	2-(Trimethylsiloxy)-1,3-Cyclohexadiene
CAS No.	54781-19-0
Molecular Formula	C9H16OSi
Molecular Weight	168.31 g/mol
Synonyms	1,3-Cyclohexadien-2-ol, trimethylsilyl ether; 2-Trimethylsiloxy-1,3-cyclohexadiene; 1,3-Cyclohexadiene-2-yloxy(trimethyl)silane; Trimethyl(1,3-cyclohexadien-2-yloxy)silane; 2-(Trimethylsilyloxy)-1,3-cyclohexadiene; 2-OTMS-1,3-cyclohexadiene; Cyclohexadienyl trimethylsilyl ether
EINECS	Contact for details

Quality Control

Our 2-(Trimethylsiloxy)-1,3-Cyclohexadiene is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.