Description

2,2,4,9,9,11-Hexamethyltetraaza-14-Crown-4 Hydrate is a specialized macrocyclic polyamine ligand, a member of the tetraazacrown ether family. Its value lies in its selective metal ion complexation properties, particularly for transition and alkali metal ions, making it a critical component in advanced chemical synthesis and separation processes. This compound is essential for researchers and manufacturers in the fields of coordination chemistry, catalysis, and sensor technology, where precise molecular recognition is required.

Application

• Selective Ion Extraction & Separation: Used as a chelating agent in liquid-liquid extraction processes for the selective recovery of specific metal ions from complex mixtures.
• Catalysis: Serves as a ligand to stabilize metal catalysts, enhancing activity and selectivity in organic synthesis reactions, including cross-coupling and oxidation.
• Chemical Sensor Development: A key component in the design of ion-selective electrodes (ISEs) and optical sensors for the detection of metal cations in analytical and environmental monitoring.
• Pharmaceutical Intermediate Synthesis: Employed in the synthesis of complex molecules where controlled metal coordination is necessary for specific reaction pathways.
• Wastewater Treatment: Applied in advanced treatment systems for the targeted removal of heavy metal contaminants.
• Academic & Industrial Research: A fundamental reagent for studying host-guest chemistry, supramolecular assembly, and ion transport mechanisms.

Basic Information

Item	Details
Product Name	2,2,4,9,9,11-Hexamethyltetraaza-14-Crown-4 Hydrate
CAS No.	54622-44-5
Molecular Formula	C₁₄H₃₂N₄O₂ • xH₂O
Molecular Weight	288.43 g/mol (anhydrous basis)
Synonyms	1,4,8,11-Tetraazacyclotetradecane, 2,2,4,9,9,11-hexamethyl-, hydrate; Hexamethyltetraazacyclotetradecane hydrate; TET A (derivative); TM TACN derivative; 14-Membered tetraaza macrocycle; Cyclam derivative; 54622-44-5 (Hydrate)
EINECS	Contact for details

Quality Control

Our 2,2,4,9,9,11-Hexamethyltetraaza-14-Crown-4 Hydrate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.