Description

7,8,9,10-Tetrahydro-3-[5-(p-Fluorophenyl)-1,2-Dimethylpentyl]-6,6,9-Trimethyl-6H-Dibenzo[B,D]Pyran-1-Ol is a high-purity synthetic cannabinoid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical reference standard and key intermediate for the synthesis of novel therapeutic agents targeting the endocannabinoid system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in neuropharmacology and medicinal chemistry.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in the production of cannabinoid-based APIs.
• Medicinal Chemistry Research: Serves as a crucial building block or precursor for synthesizing novel cannabinoid receptor ligands with potential therapeutic applications.
• Preclinical Studies: Employed in in vitro and in vivo studies to investigate pharmacokinetics, pharmacodynamics, and structure-activity relationships (SAR).
• Metabolite Synthesis: Used for the synthesis of potential human or animal metabolites required for comprehensive drug safety and efficacy profiling.
• Forensic Analysis: Acts as a certified reference material (CRM) for the accurate identification and quantification of synthetic cannabinoids in forensic toxicology.

Basic Information

Product Name	7,8,9,10-Tetrahydro-3-[5-(p-Fluorophenyl)-1,2-Dimethylpentyl]-6,6,9-Trimethyl-6H-Dibenzo[B,D]Pyran-1-Ol
CAS No.	54540-76-0
Molecular Formula	C29H37FO2
Molecular Weight	436.61 g/mol
Synonyms	1-Hydroxy-3-(5-(4-fluorophenyl)-1,2-dimethylpentyl)-6,6,9-trimethyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromene; BAY 38-7271; (-)-KN 38-7271; KN-38,7271; KN 38-7271; BAY-38-7271; (-)-(R)-3-(2-Hydroxy-4-(4-fluorobenzyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol (related stereoisomer); A synthetic cannabinoid receptor agonist.
EINECS	Contact for details

Quality Control

Our 7,8,9,10-Tetrahydro-3-[5-(p-Fluorophenyl)-1,2-Dimethylpentyl]-6,6,9-Trimethyl-6H-Dibenzo[B,D]Pyran-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic data, and the material is suitable for use as a pharmaceutical reference standard. Custom synthesis and purification to meet specific pharmacopeial or internal specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool, and well-ventilated area. Keep the container sealed under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.