Description

2-O,5-o-Bis(Methylsulfonyl)-1,4:3,6-Dianhydro-D-Iditol is a specialized, high-purity chemical intermediate of significant interest in advanced organic synthesis. Its unique bicyclic structure and sulfonyl groups make it a valuable chiral building block for the development of complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for nucleoside analogs and other complex therapeutic agents.
• Fine Chemical Synthesis: Used as a versatile precursor for constructing complex molecular architectures in custom synthesis and process optimization projects.
• Glycomimetics Research: Acts as a scaffold in the synthesis of carbohydrate mimetics and other biologically relevant sugar derivatives for biochemical studies.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective reactions to introduce specific stereocenters.
• Polymer Chemistry: Potential use as a monomer or cross-linking agent for creating specialty polymers with specific functional properties.

Basic Information

Product Name	2-O,5-o-Bis(Methylsulfonyl)-1,4:3,6-Dianhydro-D-Iditol
CAS No.	54522-27-9
Molecular Formula	C8H14O8S2
Molecular Weight	302.32 g/mol
Synonyms	1,4:3,6-Dianhydro-2,5-di-O-methylsulfonyl-D-iditol; 2,5-Di-O-methanesulfonyl-1,4:3,6-dianhydro-D-iditol; D-Iditol, 1,4:3,6-dianhydro-2,5-bis-O-(methylsulfonyl)-; 2,5-Bis-O-(methylsulfonyl)-1,4:3,6-dianhydro-D-iditol; Isosorbide 2,5-dimethanesulfonate; 2,5-Dimesylisosorbide; Isosorbide-2,5-dimesylate
EINECS	Contact for details

Quality Control

Our 2-O,5-o-Bis(Methylsulfonyl)-1,4:3,6-Dianhydro-D-Iditol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and cGMP environments where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.