Description

(+)-cis-2-Oxabicyclo[3.3.0]Oct-6-En-3-One CAS NO 54483-22-6 is a high-purity, chiral bicyclic lactone compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique fused oxabicyclic structure makes it a valuable building block for constructing complex molecular architectures with precise stereochemistry. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and novel chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, nucleoside analogs, and other bioactive molecules requiring specific stereochemistry.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce defined stereocenters.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where its rigid bicyclic framework is advantageous.
• Academic & R&D: Serves as a model compound in methodological development for ring-opening and functionalization reactions of strained heterocycles.
• Material Science Research: Investigated as a monomer or precursor for synthesizing polymers with specific thermal or optical properties.

Basic Information

Product Name	(+)-cis-2-Oxabicyclo[3.3.0]Oct-6-En-3-One
CAS No.	54483-22-6
Molecular Formula	C7H8O2
Molecular Weight	124.14 g/mol
Synonyms	(+)-cis-2-Oxabicyclo[3.3.0]oct-6-en-3-one; (3aS,6aR)-3a,4,6,6a-Tetrahydro-2H-cyclopenta[b]furan-2-one; (+)-cis-Bicyclo[3.3.0]oct-6-ene-2-one, 2-oxa-; (3aS-cis)-Hexahydro-2H-cyclopenta[b]furan-2-one; Corey Lactone derivative; Chiral Bicyclic Lactone
EINECS	Contact for details

Quality Control

Our (+)-cis-2-Oxabicyclo[3.3.0]Oct-6-En-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.