Description

4-(4,5-Dihydro-1,3-Oxazol-2-Yl)Aniline CAS NO 54472-46-7 is a versatile organic intermediate featuring a reactive aniline group linked to a 4,5-dihydrooxazole (oxazoline) ring. This unique bifunctional structure makes it a valuable building block for synthesizing complex molecules, particularly in the development of pharmaceuticals and advanced materials. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring aniline and heterocyclic motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral oxazoline-based ligands, which are crucial in asymmetric catalysis for producing enantiomerically pure compounds.
• Polymer and Material Science: Incorporated into polymer backbones or as a functional modifier to impart specific chemical or physical properties to advanced materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and pigments due to its aromatic amine functionality.
• Research & Development: A valuable tool for medicinal and synthetic chemists in academic and industrial settings for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	4-(4,5-Dihydro-1,3-Oxazol-2-Yl)Aniline
CAS No.	54472-46-7
Molecular Formula	C9H10N2O
Molecular Weight	162.19 g/mol
Synonyms	2-(4-Aminophenyl)-4,5-dihydro-1,3-oxazole; 2-(4-Aminophenyl)-2-oxazoline; 4-(4,5-Dihydrooxazol-2-yl)aniline; 4-(2-Oxazolin-2-yl)aniline; 4-Aminophenyloxazoline; 2-(p-Aminophenyl)-4,5-dihydrooxazole; 54472-46-7; 4-(4,5-Dihydro-1,3-oxazol-2-yl)benzenamine
EINECS	Contact for details

Quality Control

Our production of 4-(4,5-Dihydro-1,3-Oxazol-2-Yl)Aniline adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.