Description

3-Oxo-3-(2,4,6-Trimethylphenyl)Propionic Acid is a specialized organic intermediate featuring a β-keto acid structure with a sterically hindered mesityl group. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical and advanced material chemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those requiring sterically hindered aromatic ketone motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals where the mesitylene group imparts specific properties.
• Academic and Industrial Research: A valuable reagent for methodological development in organic synthesis and chemical biology studies.

Basic Information

Product Name	3-Oxo-3-(2,4,6-Trimethylphenyl)Propionic Acid
CAS No.	54458-28-5
Molecular Formula	C12H14O3
Molecular Weight	206.24 g/mol
Synonyms	3-Mesityl-3-oxopropanoic acid; 3-Oxo-3-mesitylpropanoic acid; β-Oxomesitylpropionic acid; 2,4,6-Trimethylbenzoylacetic acid; 3-(2,4,6-Trimethylphenyl)-3-oxopropanoic acid; Mesitylglyoxylic acid, methylene derivative; 3-(Mesityl)-3-oxopropionic acid
EINECS	Contact for details

Quality Control

Our 3-Oxo-3-(2,4,6-Trimethylphenyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail specifications and results from techniques including HPLC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases, oxidizing agents, and sources of heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.