Description

Methyl 2-O,3-o-Bis(Trimethylsilyl)-4-O,6-o-(Methylboranediyl)-α-D-Glucopyranoside is a sophisticated, organosilicon-protected carbohydrate derivative featuring a unique methylboranediyl bridge, primarily utilized as a key synthetic intermediate in advanced organic and medicinal chemistry. Its value lies in providing precise stereochemical control and protecting group strategies for the synthesis of complex glycomimetics and nucleoside analogs. This high-purity building block is essential for researchers and process chemists in pharmaceutical R&D, agrochemical discovery, and specialized fine chemical production who require reliable, high-quality intermediates for complex multi-step syntheses.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside analogs, antiviral agents, and carbohydrate-based therapeutics.
• Glycomimetics Synthesis: Used in the preparation of structurally complex sugar mimics for drug discovery and biological probe development.
• Agrochemical Research: Serves as a precursor in the development of new active ingredients with specific stereochemical requirements.
• Chemical Biology Tool: Employed in the synthesis of labeled or modified sugars for studying carbohydrate-protein interactions and metabolic pathways.
• Process Chemistry: Used in scale-up and optimization of synthetic routes for high-value fine chemicals and active pharmaceutical ingredients (APIs).
• Academic Research: A valuable reagent for methodological development in synthetic organic chemistry, particularly in stereoselective synthesis and protecting group chemistry.

Basic Information

Item	Details
Product Name	Methyl 2-O,3-o-Bis(Trimethylsilyl)-4-O,6-o-(Methylboranediyl)-α-D-Glucopyranoside
CAS No.	54400-90-7
Molecular Formula	C16H37BO6Si2
Molecular Weight	392.45 g/mol
Synonyms	Methyl 2,3-Bis-O-(trimethylsilyl)-4,6-O-(methylboranediyl)-α-D-glucopyranoside; α-D-Glucopyranoside, methyl 2,3-bis-O-(trimethylsilyl)-4,6-O-(methylboranediyl)-; Methyl 2,3-di-O-trimethylsilyl-4,6-O-methylboranediyl-α-D-glucopyranoside; 54400-90-7; Silyl-protected glucopyranoside boronate; Methylboranediyl-bridged glucoside; TMS-protected glucopyranoside boronic ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-O,3-o-Bis(Trimethylsilyl)-4-O,6-o-(Methylboranediyl)-α-D-Glucopyranoside is manufactured under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Our products are supported by a full suite of analytical data including NMR (1H, 13C, 11B), HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.