Description

1-Mesitylenesulfonyl-1,2,4-Triazole is a specialized sulfonylation reagent and versatile synthetic intermediate used in organic synthesis. This compound matters for its role in introducing the mesitylenesulfonyl (Mts) protecting group, particularly in peptide synthesis and the preparation of complex pharmaceutical molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing nitrogen-containing heterocycles and facilitating selective chemical transformations.

Application

• Peptide Synthesis: Used as a coupling agent and for introducing the Mts (2,4,6-trimethylbenzenesulfonyl) protecting group for amines.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) containing triazole or sulfonamide motifs.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Utilized in the synthesis of polymers, ligands for catalysis, and other functional organic materials.
• Chemical Biology: Acts as a reagent for bioconjugation and probe synthesis due to its reactivity with nucleophiles.
• General Organic Synthesis: Functions as a sulfonylating agent for alcohols, amines, and other heteroatoms in multistep synthetic routes.

Basic Information

Product Name	1-Mesitylenesulfonyl-1,2,4-Triazole
CAS No.	54230-59-0
Molecular Formula	C11H13N3O2S
Molecular Weight	251.30 g/mol
Synonyms	1-(2,4,6-Trimethylbenzenesulfonyl)-1H-1,2,4-triazole; 1-Mesitylsulfonyl-1,2,4-triazole; Mts-Triazole; 1H-1,2,4-Triazole, 1-[(2,4,6-trimethylphenyl)sulfonyl]-; 1-(Mesitylenesulfonyl)-1H-1,2,4-triazole; 1-(2,4,6-Trimethylphenylsulfonyl)-1,2,4-triazole; Mesitylenesulfonyl triazole
EINECS	Contact for details

Quality Control

Our 1-Mesitylenesulfonyl-1,2,4-Triazole is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.