Description

Ethanone, 2-Chloro-1-Cyclobutyl- (9Ci) is a specialized organic building block featuring a cyclobutyl ketone core functionalized with a reactive chlorine substituent. This compound matters as a versatile intermediate for synthesizing more complex molecules, particularly in pharmaceutical and agrochemical research where the strained cyclobutane ring can impart unique biological activity. It is needed by R&D chemists and process development scientists in fine chemical, pharmaceutical, and advanced material industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging its reactive halogen for coupling reactions.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers or cross-linkers for polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	Ethanone, 2-Chloro-1-Cyclobutyl- (9Ci)
CAS No.	54195-75-4
Molecular Formula	C6H9ClO
Molecular Weight	132.59 g/mol
Synonyms	2-Chloro-1-cyclobutylethanone; 2-Chloro-1-cyclobutyl-ethanone; 1-Cyclobutyl-2-chloroethanone; 2-Chloro-cyclobutyl methyl ketone; α-Chlorocyclobutyl methyl ketone; NSC 403119; 2-Chloro-1-cyclobutyl-ethan-1-one
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Chloro-1-Cyclobutyl- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. Handle and store under an inert atmosphere if prolonged storage is required to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.