Description

Fenbendazole Sulfone is a key pharmaceutical intermediate and metabolite of the broad-spectrum anthelmintic agent, fenbendazole. This compound is of significant importance for quality control, research, and development within the veterinary and pharmaceutical sectors. It serves as a critical reference standard for analytical testing and as a precursor in the synthesis of advanced antiparasitic agents. Industries requiring high-purity chemical standards, including pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories, rely on this material for its consistency and reliability.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of fenbendazole in drug products and raw materials via HPLC, LC-MS, or other analytical methods.
• Veterinary Drug Metabolite Studies: Essential for pharmacokinetic and metabolic pathway research to understand the efficacy and safety profile of fenbendazole treatments in animals.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed in the synthesis and development of new or improved anthelmintic formulations.
• Quality Control & Assurance: Critical for in-house QC laboratories to validate analytical methods, ensure batch-to-batch consistency, and comply with regulatory guidelines (e.g., FDA, EMA, VICH).
• Academic and Industrial Research: Used in biochemical and pharmacological research to study parasite resistance mechanisms and develop new therapeutic strategies.

Basic Information

Item	Details
Product Name	Fenbendazole Sulfone
CAS No.	54029-20-8
Molecular Formula	C₁₅H₁₃N₃O₅S
Molecular Weight	347.35 g/mol
Synonyms	Fenbendazole Sulfone; [5-(Phenylsulfonyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester; Methyl [5-(phenylsulfonyl)-1H-benzimidazol-2-yl]carbamate; Fenbendazole S,S-dioxide; Fenbendazole Sulfoxide (Note: often confused, but sulfone is the further oxidized form); HOE 881V; NSC 339312; Panacur Sulfone
EINECS	Contact for details

Quality Control

Our Fenbendazole Sulfone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by IR and HPLC, assay determination, and control of related substances and residual solvents, to ensure it meets high-purity standards suitable for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.