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Albendazole S-Oxide CAS NO 54029-12-8


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CAS No.:54029-12-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Albendazole S-Oxide is a key pharmaceutical intermediate and metabolite of the broad-spectrum anthelmintic drug Albendazole. This compound is critical for research and development in veterinary and human parasitology, serving as a direct precursor in synthesis pathways and a reference standard for analytical studies. It is primarily utilized by manufacturers of active pharmaceutical ingredients (APIs), contract research organizations (CROs), and analytical laboratories focused on antiparasitic drug development and quality control.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of Albendazole and related benzimidazole anthelmintic APIs.
  • Reference Standard: Used as a high-purity certified reference material (CRM) for analytical method development, validation, and quality control testing of Albendazole-based products.
  • Metabolite Studies: Essential for pharmacokinetic and metabolic pathway research to understand the efficacy and safety profile of Albendazole.
  • Veterinary Medicine Production: Incorporated into the manufacturing process of antiparasitic formulations for livestock and companion animals.
  • Research & Development: Serves as a building block in medicinal chemistry for developing new benzimidazole derivatives with improved therapeutic profiles.

Basic Information

Product Name Albendazole S-Oxide
CAS No. 54029-12-8
Molecular Formula C12H15N3O3S
Molecular Weight 281.33 g/mol
Synonyms Albendazole Sulfoxide; Albendazole Oxide; [5-(Propylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester S-oxide; Albendazole Metabolite; Ricobendazole (as the sulfoxide form); Methyl 5-(propylsulfinyl)-1H-benzimidazol-2-ylcarbamate; Albendazole Sulphoxide; ABZ-SO
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Quality Control

Our Albendazole S-Oxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and purity, and identification by IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time corresponds to reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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